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Human LAG-1/CCL4L1

品牌：翌圣生物
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翌圣生物科技(上海)股份有限公司更新時(shí)間：2024-12-24 09:03:45

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詳細(xì)介紹

LAG-1 is CC chemokine that signals through the CCR5 receptor. LAG-1 is identical to MIP-1β (ACT II isotype) except for two amino acid substitutions; arginine for histidine at position 22 and serine for glycine at position 47 of the mature protein. LAG-1 chemoattracts monocytes, and exhibits activity as an HIV-suppressive factor.

Product Properties

Synonyms	CCL4L1
Accession	Q8NHW4
GeneID	388372
Source	E.coli-derived Human CCL4L1 protein,Ala24-Asn92.
Molecular Weight	Approximately7.8 kDa
AA Sequence	APMGSDPPTA CCFSYTARKL PRNFVVDYYE TSSLCSQPAV VFQTKRGKQV CADPSESWVQ EYVYDLELN
Tag	None
Physical Appearance	Sterile Filtered White lyophilized (freeze-dried) powder.
Purity	> 97% by SDS-PAGE and HPLC analyses.
Biological Activity	Fully biologically active when compared to standard. The ED₅₀ as determined by a cell proliferation assay using human CCR5 transfected murine BaF3 cells is less than 2.0 ng/mL, corresponding to a specific activity of > 5.0 × 10⁵ IU/mg.
Endotoxin	<0.1 EU/μg of protein as determined by LAL method.
Formulation	Lyophilized from a 0.2 μm filtered concentrated solution in PBS.
Reconstitution	We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1 % BSA to a concentration of 0.1-1.0 mg/mL. Stock solutions should be apportioned into working aliquots and stored at ≤ -20 °C. Further dilutions should be made in appropriate buffered solutions.